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J.T.Baker® Cell Lysis Solution & Endonuclease

Sustainable solutions to streamline and scale your harvest process

J.T.Baker® chemicals and products are REACH-compliant and readily biodegradable to provide sustainable and scalable solutions for the clarification process. These highly effective, ready-to-use reagents streamline workflows and reduce process challenges, allowing you to scale up production while maintaining superior performance and efficiency.

Avantor’s innovative J.T.Baker® Cell Lysis Solution and Endonuclease are designed to work together to provide an efficient and sustainable solution for scaling up biopharma processes. These high-performance reagents ensure you adhere to current good manufacturing practices (cGMP) while maintaining full regulatory compliance. Optimizing cell lysis and DNA extraction can streamline workflows, reduce waste and improve small- and large-scale production productivity.

Sustainable

Achieve the same high cell lysis efficiency as Triton™ X-100, without the environmental toxicity risks or regulatory hurdles. Our eco-friendly alternative delivers reliable performance while supporting sustainability and complying with changing regulation

Flexible

These highly concentrated, ready-to-use products provide flexible storage options and require less reagent volume to reduce preparation time and optimize lab efficiency. Their adaptability makes them ideal for many biopharma applications to streamline workflows and improve productivity.

Scalable

J.T.Baker® Cell Lysis Solution and Endonuclease are available in various sizes and are of cGMP-grade quality. They offer superior convenience, supply chain security and easy scalability. They provide consistent performance and reliable support for scaling up production.

Quality

Our compatible products provide reliability to efficiently harvest high-quality viral vectors and remove impurities without compromising viral titer. They are optimized for maximum yield and purity and to support critical viral vector production processes in biopharma applications.

Webinar: Learn how to optimize the cell lysis step and improve rAAV recovery

Review the research behind this readily biodegradable, ready-to-use cell lysis alternative that requires no preparation or refrigeration while preserving viral vector integrity. This solution shows improved protection of particles during agitation, as well as flexible process development with reduced foaming and viscosity for consistent performance in viral vector production.

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White paper: A sustainable alternative to Triton™ X-100 for scalable cell lysis

J.T.Baker® Cell Lysis Solution provides a chemical lysis alternative that is European Chemical Agency and REACH compliant. This white paper shows how it matches performance across various process conditions with minimal impact on viral vector integrity, clears from the downstream process and is compatible with endonuclease, resulting in quality, potent vectors.

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Get your free sample: Test our high-performance solutions

You can experience our compatible products' superior quality and performance with a free sample, available for a limited time. Our high-concentration formulation reclaims bioreactor space by reducing viscosity and foam generation, delivering significant cost, time and labor savings. Optimize your biopharma processes with this efficient solution.

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Ready to scale up your gene therapy development?

Choose safer, more efficient solutions for viral vector harvest and clarification from Avantor. Our range of modular and scalable products ensures consistent quality, supply chain security and regulatory documentation support. Streamline your gene therapy development with a trusted partner to accelerate your process while maintaining high compliance and performance standards.